Gastrointestinal chemotaxis 2 plus sign is more serious, may cause malignant changes, it is recommended to give timely treatment. Gastrointestinal chemotaxis 2 plus belongs to moderate intestinal chemosis, which is a pathological state in which gastric mucosal epithelial cells are replaced by intestinal cells, and is mostly seen in chronic atrophic gastritis in clinic, which belongs to gastric precancerous lesions, and has the possibility of further developing into gastric cancer. Gastric mucosa with moderate enterochemistry is more serious, if there is Helicobacter pylori infection, omeprazole, amoxicillin, clarithromycin, bismuth potassium citrate and other drugs can be given to eradicate Helicobacter pylori. If there is no H. pylori infection, acid inhibiting drugs, such as rabeprazole, pantoprazole, etc., can be given, together with gastric mucosa protection drugs, such as aluminum thioglycollate, magnesium aluminum carbonate and other drugs for treatment. The above drugs should be used under the guidance of specialized physicians. Gastric mucosa moderate intestinal dysplasia patients are recommended to prohibit smoking, alcohol, spicy food, diet should be light, easy to digest, rich in nutrients. Patients with moderate intestinal metaplasia of gastric mucosa are advised to consult a doctor in time for early treatment under the guidance of a professional physician.