Cutting-edge concept in diabetes treatment: multiple drugs in small combinations Patients often ask me, “What are the best drugs to treat diabetes?” The pathogenesis of diabetes is multifaceted. Various drugs have different mechanisms of action. Therefore, no one drug is a “good drug”. A “good drug” should be a combination of multiple drugs, but each in a small dose. There is a new class of drugs, DDP4 and GLP-1 class, because its mechanism of action is completely new: 1, reduce insulin dosage. 2. Protect and restore the function of the islets. Diabetologists around the world are now placing high hopes on this class of drugs. It is hoped that more of these drugs will be developed to cure diabetes.