What to do if your aminotransferases are elevated with interferon?

Interferon aminotransferase is elevated, it may be caused by the adverse reaction of interferon or other factors, need to deal with the local causes.
1. Interferon adverse reactions: If the dose of interferon is greater than 1 million U per day, it will cause transaminase elevation, platelet count and granulocyte reduction, which can be quickly normalized when the drug is discontinued or the dosage is reduced. In addition, the adverse effects of interferon include skin peeling, drowsiness, hair loss and high blood pressure, etc. Interferon is prohibited for those who are allergic to interferon.
2. Other factors: active replication of hepatitis B virus can also cause transaminase elevation, in this case, you need to consider receiving antiviral therapy, the current first-line antiviral therapy is entecavir and tenofovir, etc.; dietary factors or medication factors may also cause transaminase elevation, in this case, you need to consider improving diet or stopping medication.
In addition, the use of interferon carries certain risks, and it is recommended that the patient must be under the guidance of a specialist, and should not use the drug without authorization.