After a cranial defect occurs, one is faced with cranial repair. Cranial repair is a relatively routine procedure in neurosurgery, the main purpose of which is to address the lack of effective protection of brain tissue in the defect area, blood supply disorders, abnormal cerebrospinal fluid circulation and other problems, and also to address the problem of shape repair and plastic surgery. It is not good to perform cranial repair too early or too late. What are the indications for doing cranial repair? In the neurosurgery guidelines, for patients with cranial defects caused by debridement due to intracranial hypertension, generally 2-3 months after the defect, if the defect area reaches 3*3 cm or more, it meets the characteristics of surgery and the patient needs to go to the hospital to be repaired by a specialized surgeon. Cranial bone repair is a common surgery, the implementation of which is not difficult and can be carried out in large hospitals in general places, as long as the scalp is cut, the periosteum is bluntly separated, the bone window is completely exposed, the repair prosthesis is taken and placed in the bone window and adjusted to achieve physiological anatomical reset, and the skin is sutured layer by layer. Only the surgical approach taken is different, and the results achieved are very different. At present, the common clinical practice is titanium mesh cranial repair, but because the implant material is metal titanium, the covered repair method increases the chance of postoperative rejection infection and material exposure, which makes the repair effect less ideal. Currently, the peek cranioplasty can help patients achieve the dual goals of basic repair and shape shaping. This procedure is an advanced and mature repair technique that has been studied and summarized in hundreds of pathologies and realized 4 technical innovations with rich experience and good results.