Glutamyl transpeptidase 246 U/L is usually serious. The normal value range of glutamyl transpeptidase is 3~50U/L. The current test result is 200U/L, which indicates that it is seriously high, and it is often caused by some liver and gallbladder diseases, such as acute hepatitis and alcoholic hepatitis. In addition, high glutamyl transpeptidase may also be caused by medication factors, such as antiepileptic drugs, which are likely to have a great impact on glutamyl transpeptidase, leading to its elevation several times. It is recommended to go to the hospital, do further examination, to clarify which is the cause of the disease, to take treatment for the cause of the disease, if it is caused by drugs, if necessary, need to temporarily stop the drug.