The normal value of serum copper cyanin is about 200-500 mg/L. Less than 80 mg/L is strong evidence for the diagnosis of hepatoblastoid nuclear degeneration. Hepatomegaly is an autosomal recessive disorder of copper metabolism, and common clinical manifestations include: 1. Neuropsychiatric symptoms. Examples include choreiform movements and tremors and bradykinesia. Psychiatric symptoms are super obvious and often manifest as loss of concentration and memory, intellectual disability, and emotional instability.2. Impaired liver function.3. Corneal KF ring, which means that the cornea can appear as a greenish-brown or dark brown ring. If the diagnosis of hepatomegaly is confirmed, the following treatments are needed: 1. Diet therapy. Avoid foods high in copper, such as millet, brown rice, buckwheat, beans, nuts, pumpkin, mushrooms, dried vegetables, dried fruits, crab shells, fish and shrimp, animal liver and blood, chocolate, cocoa, etc. 2. Medication. Penicillamine or dimercaptopropanesulfonic acid can be taken. 3. Symptomatic treatment. For patients with tremor, benazepam can be used; for those with myotonia and bradykinesia, dopamine preparations can be taken; for those with obvious mental disorders, olanzapine and risperidone can be taken.