Hepatomegaly is suspected when serum copper blue protein is less than 200 mg/L, and if it is less than 80 mg/L it is strong evidence for the diagnosis of hepatomegaly. Hepatomegaly is an autosomal recessive disorder in which patients have an inherited disorder of copper metabolism. Because the abnormal copper deposits cannot be eliminated from the body, it results in copper deposits in the liver and basal ganglia region. Its function is impaired, producing cirrhosis as well as degeneration of the basal ganglia leading to involuntary movements. Essentially this disease is a metabolic disorder, with symptoms characterized by Parkinson’s syndrome with dyskinesia, where patients often suffer from torsion of the hands and feet, torsion spasms, and choreiform movements. The disease usually starts in young people, and the symptoms progressively worsen. Treatment involves reducing copper intake, which can be minimized with chelating agents, and increasing copper excretion. Diagnosis relies on a copper blue protein test; normal values are 200-500 mg/L, and patients with hepatomegaly are less than 200 mg/L.