High estradiol in boys is usually caused by obesity, taking hormone-containing drugs, suffering from endocrine diseases and other factors. 1. The common cause of estradiol in boys is obesity, which will lead to more body fat, and fat metabolism will express more aromatic compounds, which will lead to the conversion of testosterone to estradiol in men. 2. Hormonal drugs: If you consume too many drugs containing hormones, then it will also lead to increased estradiol in boys. 3. Endocrine disorders: If the boy suffers from endocrine diseases, it will also lead to hormone secretion disorders, which will also lead to higher estradiol. If you find any estrogen abnormality, then it is recommended to consult a doctor in time to treat the symptoms.