Hyperthyroidism patients with leg weakness should be investigated for hyperthyroidism causing periodic hypokalemic paralysis, in which case the patient should go to the hospital immediately to clarify the blood potassium situation. If the patient is diagnosed with hypokalemic periodic paralysis, potassium supplementation therapy is needed. In mild cases, oral potassium chloride extended-release tablets or diluted potassium chloride solution can be given, and in severe cases, intravenous potassium chloride supplementation is required. The patient needs to treat the primary disease and needs to be cured of hyperthyroidism. When hyperthyroidism is cured, the hypokalemic periodic paralysis it causes does not recur.