Hypothyroidism is caused by a decrease in the synthesis and secretion of thyroid hormones by the thyroid gland. The main manifestations of hypothyroidism include weakness, fear of cold, little or no sweating, weight gain, and low metabolic symptoms such as swelling of the face and eyelids. Because typical hypothyroidism is characterized by a slow heart rate, the following points should be noted when patients with hypothyroidism have panic attacks: I. Combined arrhythmia, if patients with hypothyroidism have panic attacks, an electrocardiogram (ECG) should be done to clarify the ECG status of the panic attacks. Second, to clarify the functional status of the thyroid gland, whether there is an excessive dose of drug replacement therapy. Patients with hypothyroidism require replacement therapy with levothyroxine sodium tablets, and pharmacologic hyperthyroidism may occur when the dose of replacement therapy is too high. Patients with pharmacologic hyperthyroidism will have symptoms of panic and rapid heart rate. Third, combined with coronary heart disease, angina pectoris, etc., when hypothyroidism patients combined with coronary heart disease, angina pectoris may also appear panic, chest tightness symptoms.