The whitening of the fingertips may be a kind of Raynaud’s phenomenon. Raynaud’s phenomenon is a very common clinical symptom, refers to the patient by the cold or emotional changes and other stimuli, the skin at the end of the fingers appear white, purple or red phenomenon, and can be accompanied by numbness, pain, cold feeling. Raynaud’s phenomenon is usually secondary to rheumatic immune diseases, such as systemic lupus erythematosus, scleroderma and mixed connective tissue disease. Of course, if there is no primary disease mentioned above, it is primary Raynaud’s disease, which is common in young women, mostly in cold areas, with onset in winter and less common in summer, and the onset of the disease is more insidious. Attention to strict smoking cessation, in addition, can be applied to dilate the blood vessels of the drug symptomatic treatment.