The cause of long-headed malformation is unknown, and Converse et al. suggest that the condition is a congenital developmental malformation. The performance of the pregnant woman during pregnancy can also affect the child with long head malformation; therefore, the pregnancy period is the most critical. It is suggested that pregnant women should pay attention to the following points to reduce the occurrence of pediatric malformations 1, early pregnancy, avoid fever and cold. Women who have had high fever in early pregnancy, even if the child does not appear obvious appearance malformation, but the brain tissue development may be adversely affected, manifested as low intelligence, poor learning and reaction ability, this low intelligence can not be recovered. Of course, high fever causes fetal malformation is also related to the sensitivity of pregnant women to high fever and other factors. 2.Avoid approaching cats and dogs. Few people know that cats with bacteria are also a source of infectious disease that is very threatening to cause fetal malformation, and cat feces is the main way to spread this malignant infection. 3. Avoid women who wear heavy makeup every day. Research shows that the incidence of fetal malformations in those who wear heavy make-up every day is 1.25 times higher than those who do not wear heavy make-up. The main adverse effects on the development of fetal malformations is the arsenic, lead, mercury and other toxic substances contained in cosmetics, these substances affect the normal development of the fetus. Secondly, some of the ingredients in cosmetics produce teratogenic aromatic amine compounds after exposure to ultraviolet light from the sun. 4, avoid mental tension during pregnancy. Human emotions are controlled by the central nervous system and endocrine system, one of the endocrine adrenocorticotropic hormone and human mood changes have a close relationship. When pregnant women are emotionally stressed, adrenocorticotropic hormone may hinder the fusion of an embryonic mucosal tissue, if it occurs in the first three months of pregnancy, it will cause fetal cleft lip or cleft palate and other malformations. 5, avoid drinking alcohol. Pregnant women drink alcohol, alcohol can enter the developing embryo through the placenta and cause serious damage to the fetus. Such as a very small head, extremely small ears and nose and wide upper lip, etc. 6, avoid eating mycotoxin food. Experts pointed out that pregnant women who eat food contaminated with mycotoxin (moldy food), mycotoxins can be scourged through the placenta and the fetus, causing chromosomal breakage of cells in the fetus.