As the variety of drugs increases, people are becoming more aware of the adverse effects of drugs while recognizing the positive effects of using them. When doctors prescribe medication, they have to take into account both the therapeutic effect and the need to ensure the safety of the patient with the medication. However, as a home medication, the first thing is safety and the second thing is effectiveness. It is important to know that most drugs have more or less toxic side effects, especially when used for a long time or in larger doses, it is more likely to have toxic side effects. Family medication to avoid adverse reactions should pay attention to the following points: (1) carefully read the drug instructions. Patients should carefully read the drug instructions before taking, especially to read the indications, contraindications, dosage, adverse reactions, drug interactions, precautions and other aspects of the content, when taking drugs must comply with the relevant provisions of the instructions. (2) The dose should not be too large or too small. The dose specified in the drug instructions generally refers to the average dosage or range of dosage for adults aged 18 to 60 years old, below which there may be no efficacy and above which toxic reactions may be caused. For allergic patients, toxic reactions may also occur within a reasonable therapeutic dose range and should be noted. (3) Minimize the variety of drugs used. Many drugs do not cause toxicity in a reasonable dose range when applied alone. However, when more than five drugs are used, the side effects will increase exponentially. (4) Do not drink alcohol before or after taking medication. Alcohol contains ethanol. In addition to accelerating the metabolic transformation of certain drugs in the body and reducing their efficacy, ethanol can also induce adverse drug reactions. Long-term alcohol consumption may cause liver damage, affecting the metabolic function of the liver on drugs, so that many adverse drug reactions increase. In particular, drinking alcohol when taking drugs can cause the digestive tract to expand, increasing the absorption of drugs, which can easily cause adverse reactions. (5) The elderly, children, maternal medication should be particularly cautious. For children, domestic and foreign data show that streptomycin, kanamycin, gentamicin may damage the auditory nerve of children and cause deafness; polymyxin, norepinephrine can cause kidney damage in children; gastrofacial can cause brain damage in some children; tetracycline, haloperidol and other drugs can affect the development of teeth and bones in children. Tetracycline and haloperidol can affect the development of teeth and bones of young children, etc. Therefore, the elderly and children should be particularly careful in the selection of drugs, not to use drugs with many adverse reactions, to reduce the dosage of drugs, to avoid long-term use of drugs, and to avoid adverse drug interactions. Pregnant and lactating women use drugs, not only may I be affected by adverse drug reactions, many drugs may also damage the growth and development of children. If the condition requires the use of drugs, be sure to fully listen to the advice of medical personnel, and strictly comply with the prescribed dosage. (6) People with poor liver and kidney function should be careful when taking medication. Many drugs can aggravate liver and kidney damage, as mentioned above, such as antipyretic and analgesic drugs, anti-tuberculosis drugs, antibacterial drugs and so on. The key to which drug will cause damage to the liver or kidneys lies in the organ in which the drug is metabolized and excreted after entering the body. (7) Avoid using drugs that have had adverse reactions again. If a patient uses a drug that has had an adverse reaction again, it is possible that the drug may cause a re-stimulation and another adverse reaction because the patient is already allergic to the drug.