Causes of lower extremity weakness include conditions such as lumbar spinal stenosis, cervical spondylosis (spinal cord type), blockage of blood vessels in the lower extremities, and electrolyte disorders. 1. Lumbar spinal stenosis. Due to long-term nerve root compression, it causes abnormal sensation in the innervated area, and even muscle weakness or even inability to walk. Therefore, active treatment and, if necessary, surgery should be carried out at an early stage to avoid the possibility of leading to paralysis. 2.Cervical spondylosis (spinal cord type). Spinal cord compression can lead to muscle weakness, sensory hypersensitivity or even hypoesthesia of the limbs, and in severe cases, muscle atrophy, etc. It is recommended that at the early stage of the disease, if there is no significant relief after conservative treatment, surgical treatment can be taken according to the condition. 3, lower limb vascular blockage, venous blockage. In addition, if arterial thrombosis occurs, necrotic disease of the lower limbs will gradually appear if there is vascular thrombo-occlusive lesion at a later stage, and it is impossible to walk on the ground or even amputate the limbs. 4, electrolyte disorders. Such as hypokalemia, serious hypokalemia can lead to general weakness, mental lethargy and other clinical manifestations need to consult a doctor as soon as possible, a clear diagnosis to give active treatment to avoid delaying the disease or even life-threatening possibility. In conclusion, in addition to the above common causes of lower limb weakness, there are still many factors such as Parkinson’s disease, spinal tuberculosis and intervertebral discitis that can cause lower limb weakness. Therefore, if any discomfort occurs within a short period of time and is not relieved after rest, it is necessary to go to the hospital as soon as possible for further treatment.