Why is fasting beyond 24 hours abnormal glucose monitoring?

Core Tip: In order to ensure accurate blood test results, many blood biochemistry tests require patients to fast after dinner until the next day’s blood collection, fasting for about 12-14 hours. But excessive fasting can also affect the test results. Experts point out that if the fasting time reaches more than 24 hours, some tests will have abnormal results, such as serum bilirubin may increase due to the growth of fasting time, and blood sugar may be reduced to hypoglycemia due to excessive fasting time. Blood lipids fasting excessive, triglycerides, glycerol, free fatty acids counter have increased, while cholesterol did not change significantly, so the longer fasting time is not the better. Hypoglycemia with sympathetic excitement as the main manifestation in fasting, several hours after meal or after physical activity should be distinguished from diseases with sympathetic excitement, such as hyperthyroidism, pheochromocytoma, autonomic nerve disorder, diabetic autonomic neuropathy, menopausal syndrome, etc. Fasting for more than 24 hours may cause abnormal blood glucose monitoring In order to ensure the accuracy of blood test results, many blood biochemistry tests require patients to fast after dinner until the next day’s blood collection, fasting for about 12-14 hours. However, excessive fasting can also affect the test results. If the fasting time reaches more than 24 hours, some tests will have abnormal results, such as serum bilirubin may increase due to the growth of fasting time, and blood glucose may decrease to hypoglycemia due to excessive fasting time. Blood lipids fasting excessive, triglycerides, glycerol, free fatty acids counter have increased, while cholesterol did not change significantly, so the longer fasting time is not the better. The other 3 factors that affect blood glucose and lipid testing: First: alcohol consumption Alcohol consumption increases plasma lactate, urate, hexanal, and acetate. Long-term alcohol drinkers have high HDL cholesterol, increased mean red blood cell volume, and higher glutamyl transpeptidase (GGT) than non-drinkers, and this can even be used as a screening test for alcoholics. Second: smoking Smoking addicts, blood carbon monoxide hemoglobin content of up to 8%, while non-smokers content in 1% or less. In addition, catecholamines and serum cortisone are also higher than in nonsmokers. There were also changes in hematology, with increased white blood cell count, decreased eosinophils, increased neutrophils and monocytes, high hemoglobin, and high mean red blood cell volume. Third: drugs The effect of drugs on the test is very complex, with more than 15,000 drugs interfering with the test. It is known that anti-tuberculosis drugs, antibiotics, anti-leukemic agents, sulfonamides, have varying sizes of liver function, and even a few commonly used drugs can cause serious drug reactions. Therefore, it is the best policy to suspend all kinds of drugs before sampling and examination, and if they cannot be discontinued, you should understand the possible effects on the test results. Patients cannot monitor their blood glucose 24 hours a day, and when there is a wave in blood glucose at a certain time, the patient’s body remains compromised. Therefore, glycated glucose protein is a better test at the time of surgical review.