What to check for thalassemia

Laboratory tests such as blood test, red blood cell osmotic fragility test and other tests can be done for thalassemia. 1. Laboratory tests: Thalassemia is a hereditary hemolytic anemia caused by a mutation or deletion of the gene for the bead protein peptide chain of hemoglobin, resulting in reduced or complete absence of bead protein synthesis. Routine blood tests are the preferred method of screening for thalassemia, which is mainly characterized by microcytes and hypochromia. 2. Erythrocyte osmotic fragility test: thalassemia often presents with reduced osmotic fragility of red blood cells. 3. Other tests: Genetic analysis is required for the final diagnosis of thalassemia. There are other tests for thalassemia such as hemoglobin electrophoresis screening, etc. It is recommended to complete the tests under the supervision of a doctor.