There is no direct relationship between appendectomy and bowel cancer. In terms of location, the appendix is located at the end of the cecum, at the junction of the cecum and the large intestine, and not inside the colon or rectum where bowel cancer occurs. In terms of disease progression, appendectomy is applied to acute appendiceal lesions, whereas bowel cancer is chronic. In terms of etiology, appendectomy is performed for necrosis of appendiceal tissue caused by further development of obstruction due to lymphoid follicular hyperplasia, whereas bowel cancer is associated with increasing age, family history, and intestinal polyp lesions. In terms of incidence, appendectomy tends to be performed on young men, while bowel cancer tends to be performed on middle-aged and elderly people. Therefore, there is no direct relationship between the two. It is recommended that patients with the above conditions should go to regular hospitals for timely consultation and clear diagnosis, and if in doubt, consult with professional clinicians for standardized and reasonable treatment under the guidance of doctors, so as to avoid delaying the condition.