Urine protein 3+ can be caused by physiological factors and pathological factors, such as physiological factors generally do not need treatment, pathological factors such as primary and secondary nephropathy, etc., need to address the cause of the cause of the cause and symptomatic treatment. 1. Physiological factors: they may be caused by strenuous exercise, fever, mixing with leukorrhea, menstrual blood, semen, etc. Generally, no treatment is needed, and they can return to normal after resting or removing the causes. 2. Primary kidney disease: including glomerulonephritis, nephrotic syndrome and other diseases, can be prescribed ACEI or ARB drugs to reduce urinary protein such as Benadryl, Irbesartan tablets. Glucocorticosteroids such as prednisone and immunosuppressants such as cyclophosphamide can also be given as prescribed by the doctor; at the same time, bed rest is needed and salt intake is restricted. 3. Secondary nephropathy: such as diabetic nephropathy, hypertensive nephropathy, etc. If diabetes is the cause of urinary protein 3 +, you can follow the doctor’s advice with metformin, acarbose, insulin and other hypoglycemic drugs. For hypertension, antihypertensive drugs such as nifedipine extended-release tablets, Benadryl and other antihypertensive drugs are applied. When there is urine protein 3 +, it is recommended that the patient timely hospital consultation, under the guidance of the doctor to clarify the cause, and then targeted treatment.