For extra-large blackheads and pimples, patients can get rid of them through physical therapy, topical medication or chemical peeling therapy under the guidance of a doctor. 1. Physical therapy: For large blackheads and pimples, it is recommended that patients squeeze out the contents of blackheads and pimples through an acne squeezer under the guidance of a professional doctor. 2. Topical medication:Patients can also be treated with topical ointments under the guidance of a doctor, such as retinoic acid ointment and adapalene gel. 3. Chemical peeling method: patients can also use chemical peeling method to improve, commonly used peeling agents include fruit acid, salicylic acid, etc.. For patients with extra-large blackheads and pimples, it is recommended to go to regular hospitals or medical institutions for treatment, avoiding self-operation in order to prevent adverse reactions.