Urine protein 3+ is mostly self-healing if it is caused by functional or positional causes, but if it is caused by disease, it is usually not self-healing. Excluding pseudo-proteinuria 3+ caused by urine that is not fresh and deteriorated, the causes of positive protein can be categorized into physiological and pathological causes. Physiological causes: including functional proteinuria caused by strenuous exercise, cold, and postural proteinuria, which is mainly seen in adolescents, etc., these cases of urinary protein 3+ can be cured after removing the triggers. Pathological causes: can be seen in primary glomerulonephritis, nephrotic syndrome, diabetic nephropathy, hypertensive nephropathy, purpuric nephritis, lupus nephritis, gouty nephropathy, medication renal damage, and so on, these diseases lead to urinary protein 3 +, more suggestive of the renal function of the damage to the heavier, generally can not be self-healing. It is recommended that patients with urinary protein 3+ go to the hospital, further improve the relevant examinations, clarify the specific causes, and standardize the treatment under the guidance of professional physicians.