Infants with urethral fissures may be associated with hypospadias and encopresis in male infants, and urethral inflammation in female infants, etc. It is recommended that the relevant group of people should seek timely medical attention to clarify the appropriate cause and diagnosis. 1. Paraurethral fissures in male infants. (1) Hypospadias: this is a kind of congenital malformation that often occurs in males, that is, the urethra appears abnormal opening in the penis, scrotum and other parts of the body. The occurrence of this disease is related to the genetic factors, prenatal hormone stimulation insufficiency, and long-term stimulation by chemical agents. The main manifestation is the appearance of abnormal urethral opening in the penis, which can also be accompanied by symptoms such as penile recurvature, scrotal abnormality and abnormal urination. (2) Circumcision: the opening of the foreskin is too narrow, which makes it impossible to turn upward to reveal the head of the penis, thus leading to inflammation and infection. When the prepuce leads to local infection, there may be a fissure at the external urethral opening, thus showing the symptom of a fissure next to the urethral opening; at the same time, it may also be accompanied by localized pain, urination abnormalities, and symptoms such as foreskin incarceration. 2. Female infants with urethral fissures: mainly associated with female infants with inflammation of the urethra, trauma, etc., should be timely consultation according to the fissure of the situation to choose the appropriate treatment, such as the use of iodine povidone disinfection, avoid friction of the affected area, etc., through the active treatment of fissures can generally gradually heal. There are many reasons for babies to have a fissure next to the urethra, and it should be treated promptly.