Sleeplessness, also known as difficulty falling asleep or waking up and continuing to sleep, is the main manifestation of insomnia, commonly caused by changes in various factors such as physiological, psychological and environmental factors, as well as drugs, neuropsychiatric and somatic disorders, and may also be related to certain diseases, but not necessarily a precursor to a specific disease. Common diseases that cause insomnia are: 1. Psychiatric disorders: such as depression, anxiety, somatoform disorders, etc. For example, about 50% of the first symptoms of clinical depression is insomnia, and the most common manifestation of insomnia is early awakening, with the development of the disease, depression and insomnia will form a vicious circle, the solution to this situation is to relax and sleep, otherwise, just get up. 2, internal diseases: such as restless legs syndrome, Parkinson’s disease, plant nervous system dysfunction, etc.. For example, in patients with restless legs syndrome, the main symptom is unnamed sensory abnormalities and discomfort in both lower extremities at rest or during nighttime sleep, leading to difficulties in falling asleep and an increased number of awakenings in most patients. In summary, insomnia is a clinical disease caused by a variety of complex factors, and is not solely a precursor to a particular disease, but if the situation is serious, the treatment of insomnia should be accompanied by an examination of somatic diseases.