The common link between leukopenia, enlarged lymph nodes, and lgs syndrome is that they are all related to epilepsy in some way, as follows. 1. Leukopenia: Leukopenia is a common side effect of antiepileptic drugs, such as carbamazepine. It is recommended to review the blood count and EEG regularly to adjust the medication. 2. lymph node enlargement: if the patient has an allergic reaction to antiepileptic drugs, skin rash, lymph enlargement and other symptoms may occur, and the condition can be gradually recovered after stopping the sensitizing drugs. 3. lgs syndrome: it is a special kind of epilepsy syndrome, a kind of refractory epilepsy which is most common in children, and the commonly used drugs are sodium valproate, clonidine and so on. In conclusion, it is recommended to go to the hospital in time and follow the doctor’s instructions for treatment when the above situations occur.