The symptom of “urticaria with pharyngeal obstruction” belongs to laryngeal edema caused by urticaria. Urticaria is a common skin vascular reaction allergic skin disease, patients in contact with allergens, will cause rapid-onset immune disorders in the body, which in turn causes vasodilatation and increased vascular permeability, and ultimately local tissue (such as the skin, respiratory tract, gastrointestinal tract, etc.) mucous membrane edema, manifested in the respiratory tract is called laryngopharyngeal edema, that is, the emergence of the feeling of pharyngeal obstruction. Urticaria is triggered by allergens or other factors to mast cells as the core of the activation of a variety of inflammatory cells, the release of chemical mediators with inflammatory activity (such as histamine, 5-hydroxytryptamine, cytokines, etc.), causing vasodilatation and increase in vascular permeability, smooth muscle contraction and increased secretion of the glands, resulting in a series of local or systemic allergy symptoms of the skin, mucous membranes and so on. When the allergic reaction involves the larynx and bronchial tubes, symptoms such as pharyngeal obstruction, chest tightness, dyspnea and even asphyxia may occur. Urticaria with pharyngeal obstruction belongs to the emergency, the condition is more dangerous, if not treated in time, breathing difficulties will occur, and in severe cases, it will lead to asphyxiation, which will threaten the patient’s life. It is recommended that the patient immediately consult a doctor and follow the instructions of standardized treatment, so as not to delay the condition, resulting in adverse effects.