Itchy skin after chemotherapy for liver cancer should be searched for specific causes before choosing drug treatment. If it is caused by jaundice, anti-yellowing drugs can be applied; if the drugs cause allergy, anti-allergic drugs can be taken; if it is caused by chemotherapeutic drugs, the drugs should be adjusted. 1. Jaundice: Jaundice may occur in liver cancer, and high bilirubin may cause bile salt deposition in skin, which may cause itching of skin, at this time, we should actively use anti-yellowing medicines, and commonly used medicines are ursodeoxycholic acid and so on; 2. Skin allergy: When chemotherapy for liver cancer is administered, drug allergic reaction may sometimes occur, and the skin may develop pimples or wind bumps, which are often accompanied by obvious itching. If drug allergy is diagnosed, relevant drugs should be stopped first, and anti-allergic drugs such as cetirizine or loratadine can also be used; 3. Side effects of chemotherapeutic drugs: when itching occurs after chemotherapy for liver cancer, it is also necessary to consider whether it is autoimmune dermatitis induced by chemotherapeutic drugs, at this time, not only need to adjust the medication, but also need to consider the use of hormone to inhibit immune reaction, commonly used drugs are prednisone and so on. Thus, if itchy skin occurs after chemotherapy for liver cancer, one should actively search for the cause of the disease and use medication under the guidance of doctor.