140/100mmHg is classified as grade 2 hypertension, also called moderate hypertension. For this kind of moderate hypertension, we should start the antihypertensive treatment with drugs, and use the first-line antihypertensive drugs, such as diuretics, β-blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, and angiotensin II receptor antagonists, which are reasonably selected according to the specific conditions of the patients, and give preference to the long-lasting therapeutic drugs, and combine them with other medicines if necessary. At the same time, we should actively carry out lifestyle intervention, low-salt and low-fat diet, weight control, increase exercise, quit smoking and limit alcohol, eat fresh vegetables and fruits every day, and maintain a good state of mind. While lowering blood pressure, other cardiovascular risk factors should also be actively controlled to keep blood pressure in the target range in the long term.