Ms. Jiang is 32 years old and has been married to her husband for 3 years. The elderly in the family have been looking forward to having grandchildren as soon as possible, and the couple has been working hard to actively prepare for pregnancy, but their bellies have been slow to move. The two of them have been working hard to prepare for pregnancy, but their bellies are not moving. They went to the hospital for tests, blood tests, ultrasound, and did a lot of things, but no problems were found. After being referred to the hospital, Ms. Jiang came to the fertility clinic of Jiangsu Integrated Hospital of Traditional Chinese and Western Medicine with a thick pile of labs, and the reproductive medicine specialist, Dr. Qian Ruyun, the deputy chief physician, carefully asked her medical history, read the lab reports, and did not ask her to do any more complicated tests, but only asked Ms. Jiang to monitor her temperature at home and come back to the hospital for follow-up. Her body temperature showed that the number of days of temperature increase after ovulation was only 8-9 days, which indicated luteal insufficiency, and it turned out that Ms. Jiang’s infertility was related to luteal insufficiency. What is luteal insufficiency? In recent years, there are more and more women who are infertile, and with the opening of the second child policy, some senior women who are older than 35 years old are actively preparing to have another “little one”. However, if they have been preparing for pregnancy for a long time and still have no movement, it is inevitable that they feel bored. With the rapid development of medicine, more and more causes of female infertility have been detected, among which luteal insufficiency is easy to be ignored. Luteinizing insufficiency is a common disease among women nowadays. It is an important manifestation of female endocrine disorder and one of the important causes of female infertility. The ovaries, a gonadal organ unique to women, have a very important role in infertility. The ovaries have two functions, one is to produce eggs, including follicle development, and to discharge the eggs when they are mature. The other function is to secrete hormones necessary for the maintenance of female sexual characteristics and to act on the uterus and other places to form the menstrual cycle. The normal ovulation cycle is divided into 3 stages, namely follicular development and maturation, ovulation, and luteal formation. Under normal circumstances, within 1-2 days before ovulation, the granulosa cells in the follicle begin to luteinize, and after ovulation, luteinization forms the corpus luteum and secretes estrogen and progesterone. Secretion peaks 7-8 days after ovulation and then declines rapidly 1-2 days before menstruation. If the pituitary gland does not produce enough gonadotropins and the ovaries do not produce enough estrogen, then the follicles are not well developed. Thus, although the ovaries are able to ovulate, the normal development of the corpus luteum has to be affected, resulting in a deficiency of the whole corpus luteum leading to infertility. The natural incidence of the disorder is 5% in fertile women, 3.5%-10% in infertility, 35% in early pregnancy miscarriage and 4%-60% in habitual miscarriage. So how can we know if we have luteal insufficiency? It can be done by these methods: 1, measurement of basal body temperature: ensure 6 hours of sleep every day, first thing in the morning after waking up is to measure the temperature and record it, through 2 months of continuous testing, the normal basal body temperature: the rise is not less than 0.3 degrees Celsius, the temperature rise of not less than 12 days. 2. Diagnostic scraping: Diagnostic scraping is performed on the twenty-sixth day of the menstrual cycle, and the endometrium is taken for histological examination to observe whether the secretory endometrium is formed and whether it matches the number of menstrual cycles. If the endometrium is not secreting well or is more than 2 days behind the day of scraping, luteal insufficiency is considered. 3.Measure the progesterone in the blood one week after ovulation, its level is significantly lower than normal then it indicates luteal insufficiency. 4.Ultrasound monitoring of ovulation, the time from ovulation to menstruation should be about 14 days, if it is less than 12 days, luteal insufficiency can be diagnosed. Luteal insufficiency is mainly related to endocrine disorders. The causes of endocrine disorders are both internal and external. Such as excessive stress, depression, fear, sudden change of environment, after a long illness, and malnutrition and other factors, affecting the endocrine regulation of the cerebral cortex, or repeated uterine surgery to make the endometrium injured, the endometrium is not responsive to female hormones, reflexively affect the endocrine regulation, all these factors, will trigger the “luteal body is not healthy ” . Can I still get pregnant if I have luteal insufficiency? Luteal insufficiency is one of the main causes of female infertility, and patients with luteal insufficiency are also prone to miscarriage when they get pregnant, therefore, patients with luteal insufficiency should be adjusted before pregnancy. The most common treatment for luteal insufficiency is to supplement the progesterone deficiency in the body, usually with intramuscular injections of progesterone and oral progesterone. There is also pharmacological stimulation of luteal therapy, mainly with chorionic gonadotropin to promote follicular growth. In addition, for luteal insufficiency caused by high prolactin in the blood, prolactin-lowering drugs such as bromocriptine are used. According to TCM, the main treatment for luteal insufficiency is to tonify the kidney energy and regulate the flushing. It may also strengthen the spleen, dredge the liver, tonify the qi and blood, or eliminate blood stasis. Of course, how these drugs are applied plays a different role in the effect of treatment, and too much or too little not only fail to achieve the treatment effect that varies from person to person, but also produce certain side effects. Therefore, treatment must be carried out under the guidance of a regular hospital physician.