It is possible for a woman to become pregnant when luteal insufficiency occurs because ovulation is still present and the egg can meet the sperm to form a fertilized egg, which is then implanted in the uterine cavity. However, when luteal insufficiency occurs, the progesterone level is usually low, which may not be conducive to embryo implantation or development after implantation, i.e., biochemical pregnancy and embryonic abortion may occur. In some women, luteal insufficiency can affect ovulation and sometimes embryo implantation. During the second half of the menstrual period, progesterone should be observed. When a woman has low progesterone levels, the possibility of luteal insufficiency should be highly suspected. If a woman has a combined history of adverse pregnancy, i.e. biochemical pregnancy or embryonic abortion, more attention should be paid to progesterone levels in the second half of menstruation. If the patient presents with low progesterone levels at this time, progesterone should be given to supplement progesterone. If necessary, if a woman is pregnant, she can be treated with appropriate supplementation of fetal preservation pills to preserve the pregnancy. In women with luteal insufficiency, when pregnancy occurs, there is often a clinical history of adverse pregnancy and delivery.