Luteal insufficiency refers to the lack of fully formed corpus luteum in women’s ovaries after normal ovulation, which may affect hormone secretion and eventually lead to the occurrence of infertility or miscarriage. The main causes of this condition are follicular dysplasia, endocrine disorders, ovarian dysfunction, etc. The causes need to be determined according to the specific situation: 1. follicular dysplasia: such as polycystic ovary syndrome, pituitary prolactinoma, etc., can lead to the inability of follicles to form mature follicles, thus failing to degenerate into the corpus luteum, which can lead to luteal insufficiency or even insufficient progesterone secretion; 2. endocrine disorders: such as thyroid disease, adrenal cortical disease or emotional factors can lead to endocrine disorders, which can cause insufficient secretion of estrogen or insufficient ovulatory response induced by some drugs may lead to luteal function defects or even luteal insufficiency; 3, ovarian dysfunction: if there are ovarian developmental malformations, and some ovarian function diseases such as ovarian hypofunction, premature ovarian failure and other organic lesions, which may cause ovarian secretion function Inadequate luteal function, resulting in symptoms of luteal insufficiency. Luteal insufficiency may affect the fertilization of the egg, which may lead to miscarriage and failure to maintain a normal pregnancy. Therefore, during pregnancy, hormonal drugs can be used to improve the luteal function under the guidance of a doctor to avoid endangering your health with blind medication.