Wrinkles are the traces of age on our body, when it creeps to the corners of your mouth, creeping up your eyebrows, you have to lament the easy aging of the face, youth is easy to die. How can you make this “traces of age” erased, to hide your true age? In the modern world, there are many high-tech tools that can help you. Here is a material for wrinkle reduction. A. What is hyaluronic acid Hyaluronic acid (HA for short) is a high molecular acidic mucopolysaccharide, consisting of N-acetyl-glucosamine and D-glucuronic acid, with an average molecular weight between 100,000 and 10 million Da. HA was first isolated from the vitreous humor of bull’s eye by Meyer et al. in 1934, so it is also known as vitric acid. It is widely distributed in animals, human tissues and extracellular matrix, with high content in the vitreous humor, atrial fluid, synovial fluid, skin and umbilical cord, and generally the human body contains only about 15g of HA, without which it is impossible for people to survive. Second, the main role of hyaluronic acid 1, highly moisturizing HA like a “molecular sponge” can absorb and maintain 500 to 1000 times its own weight of water, it has stronger water retention than any other natural or synthetic polymers, HA’s water retention is one of its most important physiological functions, so it is called natural moisture retention factor. HA has high water absorption at low relative humidity and low water absorption at high relative humidity, so it has an intelligent role in regulating the water balance and keeping the skin in an ideal water content. 2.Protection and lubrication of cells HA can protect and lubricate cells, regulate the movement of cells on this viscoelastic matrix, stabilize the collagen meshwork and protect it from mechanical damage. Because HA is a natural lubricant and shock-absorbing polymer, it acts as a lubricant on the surface of tendons, tendon sheaths and mucous synovial membranes. 3.Anti-aging HA is one of the main matrix components of human skin epidermis and dermis, its physiological function is to catch a large amount of water, so that it enters the cell interstices and wraps around the collagen fibers and elastic fibers. The collagen fibers and elastic fibers that get a lot of water can be fully stretched, and the skin can maintain a good elasticity and present a smooth and soft state. As we age, cell metabolism slows down, HA production decreases, collagen fibers and elastic fibers do not get enough water and cannot be fully stretched, the volume of the dermis decreases, the skin collapses and wrinkles form. 4, skin repair HA facilitates the metabolism of nutrients and the migration of epidermal cells, thus helping the skin to repair damage and reduce scars. 5.Multiple protection HA can be seen as a huge “anion group”, which can effectively reduce the transmission of ultraviolet light through the skin, reduce the formation of free radicals, reduce the degradation of collagen fibers and elastic fibers. The application of hyaluronic acid in beauty HA can be widely used in beauty and skin care, skin rejuvenation and anti-aging cosmetics, skin anti-wrinkle and wrinkle products and other fields. 1.skin care, water locking and moisturizing Japan Shiseido industrialized the production of hyaluronic acid by fermentation method in the mid-1980s, and successfully applied it in the production of cosmetics. Nowadays, HA has become one of the ace moisturizing ingredients for many high-grade skin care brands. Anti-wrinkle care With the in-depth research on HA in recent years, individual companies with high-tech research and development power began to focus on the anti-wrinkle function of HA and successfully developed related products into the market. 2.Plasticity Injection anti-wrinkle That is, using a syringe, HA is injected into the location that needs to be filled through a needle to support the collapsed skin from the inside. It can be used for the filling of facial wrinkles and folds. Since HA is composed entirely of aminoglycan, there is no species specificity, and it is the body’s own structural substance, its immunogenicity is extremely low. The artificial injection of HA to fill subcutaneous tissue is biocompatible and usually does not cause inflammation and allergic reactions in the surrounding tissues, which makes it the material of choice for biological fillers. HA subcutaneous injection implantation method originated from Europe and gradually became popular in the United States, Japan, Canada, Australia and other countries, and in recent years, it has gained popularity in Taiwan, Hong Kong and other Asian regions. Injectable fillers In addition to injectable wrinkle removal, HA is also used in lip augmentation surgery and rhinoplasty, which are also praised for their high efficiency and safety.