When a patient with hepatitis B has pain in the liver area, the first thing to consider is abnormal liver function, as this can cause pain in the liver area at this time. The examination of liver function may reveal an increase in glutamic aminotransferase, glutamic oxalacetic aminotransferase, or even bilirubin. If it does not disappear at this time, other causes should be considered, such as liver cancer, which should be examined by ultrasound of the liver, intensive CT of the liver, and methemoglobin, etc. If liver tumors are found, it can also be said that they can cause pain in the liver area. If there is still pain in the liver area even after liver tumor is ruled out, it means that the cause of pain in the liver area is not particularly serious, and it is likely to be functional, which can be regulated by taking traditional Chinese medicine and applying some drugs to dredge liver and Qi, invigorate blood circulation and relieve pain, which can often be effective. In addition, there are some patients who have pain in the liver area because of the pain in the stomach. In this case, if the liver is simply treated, the symptom of pain in the liver area cannot be solved, and the application of drugs to protect the stomach is needed to solve the pain.