Does taking various medications for a long period of time have an effect on chronic constipation?

Taking various medications for a long period of time can have an effect on chronic constipation.
Constipation refers to a feeling of difficulty in defecation, mainly manifested as a decrease in the number of bowel movements and dry and hard feces, usually due to feces moving too slowly in the digestive tract or when it cannot be effectively removed from the rectum, resulting in dehydration, hardness and dryness of feces, which triggers constipation. Long-term constipation may be associated with organic factors such as rectal and anal pathology, as well as functional factors such as disorders of the colonic transport and defecation function.
Long-term consumption of various medications, such as antidepressants like fluoxetine, calcium channel blockers like nifedipine, anti-acetylcholine drugs like atropine and opioids like pethidine, may lead to constipation or aggravate constipation, so patients are not advised to consume a variety of medications for a long period of time, and the above medications should be consumed under the direction of a doctor without authorization. Once the symptoms of long-term constipation occurs, it is recommended to consult a doctor in time to clarify the diagnosis and carry out targeted treatment.