Fluoxacin ear drops are mainly used for ear infections, and the side effects are generally minor, mainly manifested locally with the medication, as follows: 1. Pain and irritation: some patients may experience ear pain and irritation at the site of the drip; 2. Hearing changes: very few patients may also experience hearing changes, and may experience hearing loss, as well as vestibular dysfunction, which is generally rare; 3. Allergic reactions: Redness, swelling, itching, burning sensation and other related symptoms at the site of drug use may occur, and if allergic symptoms appear, use must be stopped promptly. It should be noted that if the patient has a previous allergy to quinolones, the use ofloxacin ear drops is not recommended. In conclusion, if patients experience side effects during use, it is recommended to consult a doctor or pharmacist in a timely manner.