Ofloxacin ear drops is a very widely used antibacterial type of ear drops in otolaryngology. The main ingredient is ofloxacin, which kills bacteria by acting on the A subunit of bacterial DNA helicase and inhibiting DNA synthesis and replication. Ofloxacin ear drops are clinically the most effective mainly against aerobic gram-negative bacilli, the common ones are the following bacteria, including Enterobacter aerogenes, Escherichia coli, Klebsiella, Aspergillus, Salmonella, Vibrio, etc. It is also very effective against certain penicillin-resistant Neisseria gonorrhoeae, enzyme-producing Haemophilus influenzae, etc. It is also effective against Pseudomonas aeruginosa. Clinically, it is mainly used for the treatment of acute otitis externa, suppurative otitis media and other diseases. The usage is 5-6 drops for adults each time, and an ear bath for about 10 minutes after the drops is almost enough, 3 times a day.