Jaundice is divided into physiological and pathologic, jaundice bilirubin 16 points more mg/dl more for pathological jaundice, generally can not subside by itself. Full-term infants serum total bilirubin>12.9mg/dl, preterm infants>15mg/dl can be considered as pathological jaundice. Jaundice bilirubin 16 points more mg / dl is generally pathologic jaundice, jaundice appears within 24 hours, long duration, can be progressive aggravation, the condition of severe cases can also be accompanied by neurological damage manifestations, such as depression, lethargy, anorexia, crying and restlessness, etc., may jeopardize the health of newborns organism. Jaundice bilirubin 16 points more mg/dl usually can not subside by itself, mainly through drug treatment, such as immunoglobulin, albumin, etc., light therapy to reduce the serum unconjugated bilirubin also has a certain effect. Jaundice bilirubin 16 points more mg/dl through active treatment, generally good prognosis. Jaundice big red 16 points more mg/dl, should promptly consult the doctor, the doctor to make a judgment, if necessary, give appropriate treatment. Do not blindly expect to subside on your own, so as not to delay the condition.