Betel nut stomach pain is associated with chronic gastroenteritis, cholecystitis and other factors. There are many people who have the habit of chewing betel nut, not realizing that betel nut is a more irritating food. Betel nut juice affects the body’s sense of taste and saliva secretion, leading to the impairment of the function of the digestive system. It can also irritate the stomach lining leading to inflammation of the gastric mucosa, which in severe cases can lead to gastric perforation. Frequent consumption of betel nut leads to increased secretion of gastric acid, and betel nut also contains more plant fibers, which are difficult to digest after intake and will increase the burden on the gastrointestinal tract, so there will be stomach discomfort. Cholecystitis patients who eat greasy or indigestible food in their diet, or eat betel nut will cause irritation will also cause stomach pain, so should stop taking betel nut. It is treated by medicines that protect the gastric mucosa, such as omeprazole.