Eating betel nut if there is obvious headache, belongs to the betel nut in betel nut alkali overdose and lead to poisoning. If the patient has a severe headache, must immediately go to the hospital for treatment, before arriving at the hospital can also drink a lot of warm water, take vomiting, picking the throat to wash their own stomach. After arriving at the hospital, the stomach should be washed again with a large amount of warm water or saline, and after the gastric lavage, you can apply mannitol, magnesium sulfate and other drugs for enema, or you can apply activated charcoal in the intestinal lumen for adsorption, and at the same time, you can give diuretics, such as hydrochlorothiazide, furosemide and other medicines for diuresis, and according to the patient’s condition, you can appropriately apply symptomatic detoxification drugs, such as naloxone hydrochloride, and so on. If the patient has a severe headache, a small dose of mannitol can also be injected to reduce intracranial pressure and relieve symptoms.