As we all know, most tumor diseases have the symptom of pain. Bone cancer also has such a symptom. Besides pain, what other symptoms do bone cancer patients have? Pain is the main symptom of bone tumor in early stage, which is mild and intermittent at the beginning of the disease, but gradually worsens and develops into continuous as the disease progresses. Most of the patients’ pain increases at night and affects their sleep. 2. Swelling or lump Tumor located under the periosteum or superficially appears earlier and the bone can be swollen and deformed by touch. If the tumor penetrates outside the bone, it may produce a fixed soft tissue mass with smooth or uneven surface. 3.Dysfunction When bone cancer patients are in the late stage, some functions of patients will be impaired due to pain and swelling, and there will be corresponding muscle atrophy symptoms. 4.Compression symptoms Tumor growing into the cranial cavity and nasal cavity may compress the brain and nasal tissues, resulting in cranial pressure and poor breathing; pelvic tumor may compress the rectum and bladder, resulting in difficulty in defecation and urination; spinal tumor may compress the spinal cord, resulting in paralysis. 5.Deformity Because tumor affects the development and solidity of limb bones, the deformity is obvious in lower limbs. 6.Pathological fracture As long as there is slight external force on the tumor site, it will easily cause fracture, and the swelling and pain on the fracture site will be severe. 7.Systemic symptoms Due to the consumption of tumor, stimulation of toxin and pain, a series of systemic symptoms may appear in the late stage of bone tumor, such as insomnia, irritability, loss of appetite, depression, pallor, progressive wasting, anemia and cachexia.