The age of girls for the nine-valent vaccination is 9-45 years old, and in addition to the nine-valent, they can also be vaccinated with the four-valent and two-valent, both of which are between the ages of 9-45 years old. The human papillomavirus (HPV) vaccine is mainly used to prevent HPV infection, and it is recommended to complete the vaccination between the ages of 9-45 years old, and the earlier the age of vaccination, the better the effect. The difference between the bivalent quadrivalent and the nine-valent is the different types of viruses that are prevented. Nine-valent mainly targets HPV6, 11, 16, 18, 31, 45, 52 and 58 virus subtypes; quadrivalent mainly targets lower-risk viruses HPV6 and 11, and high-risk viruses HPV16 and 18; bivalent mainly targets high-risk viruses HPV16 and 18. Pregnant women or women preparing for pregnancy should postpone vaccination until the end of pregnancy, and breastfeeding women should be cautious when receiving the vaccine. HPV vaccination is prohibited for those who have hypersensitivity to the active ingredient of the vaccine or any of the excipient components, and those who have symptoms of hypersensitivity after injection of this product should not be revaccinated with this product. Regular cervical cancer screening is still required after HPV vaccination.