Rare round low density shadow in the liver lobe with blurred borders, about 4.3 in diameter, CT value 49 is associated with fatty liver, hepatic cysts, hepatocellular carcinoma, hepatic hemangioma, and hepatic abscess. The diagnostic term rounded hypodense shadow within the liver may appear in the description of the lesion on ultrasound and CT in imaging, and any lesion in the liver with a density lower than that of the liver tissue is called a hypodense shadow, which can be seen in liver cysts, hepatic hemangiomas, nodular steatohepatitis, hepatic abscess, hepatocellular carcinoma, and a number of other liver diseases. A diameter of about 4.3 and a CT value of 49 means that the extent of the occupying lesion in the liver is 4.3 cm. The normal range of CT values for mild fatty liver is 39 to 60 Hu, and a CT value of 49 indicates that mild fatty liver may be present. Liver lobe rare round low density shadow, border blurred, diameter of about 4.3, CT value of 49 may also have other causes, it is recommended to improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.