Cephalosporin and acetaminophen tablets can generally be taken together, but should be under the guidance of a doctor. Cephalosporin is a cephalosporin antibiotic with broad-spectrum antimicrobial effect, used for the treatment of drug-resistant Staphylococcus aureus and certain gram-negative bacilli caused by infections, such as lung infections, urinary tract infections, sepsis, meningitis and so on. Acetaminophen tablets are nonsteroidal antipyretic and analgesic drugs used to treat fever caused by the common or influenza and to relieve mild to moderate pain. No adverse reactions have been found to occur when the two are taken together. Patients are advised to use the medication wisely under the guidance of a doctor. Adverse reactions to acetaminophen tablets: occasional rash, itching, urticaria, drug fever, leukopenia, thrombocytopenia, bruising or bleeding of undetermined cause; rare angioedema, lip, tongue, throat or facial edema, desquamation, oral ulcers; sometimes accompanied by bronchospasm; long-term large amounts of medication can lead to abnormalities of hepatic and renal function; overdose can lead to serious liver injury. In addition, patients who are allergic to acetaminophen tablets are prohibited, and those with severe hepatic and renal insufficiency are prohibited. The common adverse reaction of cephalosporin is allergic reaction, such as rash, urticaria, drug rash, eosinophilic leukocytosis and other symptoms, and a few patients will have anaphylactic shock. In addition, it is contraindicated in patients who are allergic to cephalosporin antibiotics. If you need to use cephalosporin and acetaminophen tablets, it is recommended to consult a professional doctor and follow the doctor’s instructions to standardize the treatment, and not blindly use the drug on your own.