When the scabies mite is infected it survives and multiplies in the folds of the body, such as the creases of the fingers, elbows, areolas, armpits, and external genitalia. The main manifestations are pimples, papules, and scabies nodules with intense itching. 1. Papule: a lesion about the size of a grain of rice, light red or normal skin color, may have an inflammatory red halo. 2. Papules: about the size of a grain of rice, with small blisters at the tip, most often found in the crevice of the fingers, wrists and other places. 3. Scabies nodules: for in the scrotum, penis, glans, etc. can be found in the diameter of less than 5mm dark red nodules, is the scabies mite death produced by the foreign body reaction. 4. Itching: the itching is intense, is due to the scabies mites move in the skin when the stimulation of nerve endings. Scabies mites are highly active at night, so itching is more serious at night. In addition to the above performance, if secondary bacterial infection can occur impetigo, folliculitis and so on. Scabies mite infection is transmissible, once infected with scabies mites need to seek medical attention, immediate isolation, targeted treatment and therapy. Note that family members or people living in groups should be treated at the same time.