It is one of the most common benign diseases of the female reproductive organs and one of the most common tumors in the human body, also known as fibromyoma and uterine fibroid. The disease is mainly due to the proliferation of smooth muscle cells in the uterus, so there is a small amount of fibrous connective tissue as a kind of supporting tissue, so it is more accurate to call it smooth muscle tumor. The etiology of this disease is still not well understood and may involve a complex interaction between cellular mutations in the normal muscle layer, sex hormones and local growth factors. Based on a large number of clinical observations and experimental results, it has been shown that uterine fibroids are hormone-dependent tumors and that estrogen is the main factor contributing to the growth of fibroids. It is also believed that growth hormone is also related to the growth of fibroids, and growth hormone can promote the growth of fibroids in cooperation with estrogen to promote mitosis, and it is speculated that human placental prolactin can also promote mitosis in cooperation with estrogen. In addition, ovarian function and hormone metabolism are regulated by the control of higher nerve centers, so the nerve center activity may also play an important role in the development of leiomyoma.