The greatest hazards of transfusing human albumin are the occurrence of allergic reactions and the development of acute heart failure. Human blood albumin is a plasma product mainly used for shock caused by blood loss trauma and burns; cerebral edema and increased cranial pressure caused by injury; edema or ascites caused by cirrhosis of the liver and renal disease; prevention and treatment of hypo-proteinemia; hyperbilirubinemia in newborns and so on.
During the use of human albumin, the following kinds of adverse reactions are likely to occur.
1. Allergic reaction: because human blood albumin is a blood product, after transfusion into the human body, there is still a possibility of allergic reaction, the chance of occurrence is small, but it is often more serious. It can be manifested as fever, chills or the appearance of skin rashes.
2. Acute heart failure: albumin will increase the osmotic pressure of the blood, will make the intracellular water to the extracellular permeability, which will increase the heart load, resulting in increased cardiac load, which can cause acute heart failure, so albumin is often slowly transfused.
If the drug is to be used, it needs to be applied correctly under the guidance of a doctor.