Soreness in the knee when the weather changes can be caused by trauma, knee synovitis, rheumatoid arthritis, etc. 1. Trauma: Trauma to the knee area causes damage to the meniscus, ligaments, synovial membrane and other tissues, which can cause soreness when the weather changes, and in severe cases, can also lead to limited knee joint movement. 2. Knee synovitis: it may be related to chronic strain injury, which causes aseptic inflammation in the synovial area. When the knee is stimulated by cold wind during weather changes, the aseptic inflammation will be aggravated, which will cause knee pain. 3. Rheumatoid arthritis: it may be related to heredity, prolonged smoking, infections and other factors, and it is easily affected by temperature changes. When the weather changes, there is a big difference in temperature, and knee soreness may occur, and it may be accompanied by morning stiffness, swelling of joints and other symptoms. Sore knees when the weather changes and the symptoms persist without relief, it is recommended to go to the hospital in time.