Lidocaine cream that is compounded lidocaine cream, lidocaine spray that is lidocaine aerosol, the two are applicable to different parts, the effect is similar, there is no good or bad. 1. Compound lidocaine cream: white cream texture, the main ingredient is lidocaine, mainly for needle puncture local anesthesia or superficial surgical anesthesia. Common adverse reactions are localized erythema and edema, occasional burning sensation, itching sensation. Serious adverse reactions should be promptly informed to the doctor for treatment. 2. Lidocaine aerosol: colorless or yellowish clarified liquid. It is suitable for local anesthesia of skin and mucous membranes, such as oral extraction surgery, gastroscopy, enteroscopy, laryngoscopy for reducing reactivity. Common adverse reactions include bronchospasm, tinnitus, occasionally ventricular fibrillation, cardiac arrest. In case of serious adverse reactions, appropriate treatment should be administered immediately. It should be noted that the use of cotrimoxazole cream is contraindicated in patients with congenital or idiopathic methemoglobinemia, as well as in people who are allergic to amide local anesthetics and to any of the components of the drug. The use of lidocaine aerosol is contraindicated in patients with hypersensitivity to local anesthetics, porphyria, uncontrolled epilepsy. The use of the above medications is subject to medical advice.