To treat gastric diseases, it is often necessary to choose a reasonable time of medication for the needs of different gastric diseases and the characteristics of the mechanism of action of drugs to obtain the best results. Domperidone (morpholine), metoclopramide (gastrofluan) and cisapride are taken before meals, which have the function of enhancing peristalsis of the gastrointestinal tract, promoting the digestion of food in the stomach and coordinating the movement of the esophagus, stomach and duodenum, and have good effect on nausea, vomiting, acid reflux, belching and stuffiness after eating. They should be taken half an hour before meals so that the drug effect will reach its peak just when eating, so that the whole upper digestive tract can function normally under the action of the drug. Take some alkaline drugs after meals, such as magnesium oxide, magnesium hydroxide, magnesium trisilicate, etc., mainly on the excessive gastric acid neutralizing effect, can be taken 1-3 hours after meals, but all should not be taken for a long time, otherwise it will cause magnesium poisoning. Renal insufficiency is prohibited. Take between meals, that is, between meals. Chronic gastritis and chronic gastric ulcer disease patients are often treated with aluminum thioglycollate (gastric ulcer), misoprostol (Hiker ulcer) or Metzolim-S granules to protect the gastric mucosa. In recent years, it was discovered that the Helicobacter pylori bacteria hidden in the gastric mucosa has an incomprehensible relationship with chronic gastritis, so doctors use treatment containing colloidal bismuth citrate, Dilaudid, etc. However, because these drugs need to be in direct contact with the gastric mucosa to work, it is advisable to take them between meals. Antacids such as cimetidine (metformin, Tagamet), ranitidine, famotidine and omeprazole (Loxac) are drugs that strongly inhibit the secretion of gastric acid. They can not only relieve the pain caused by ulcers or gastric mucosal erosion and promote ulcer healing, but also treat upper gastrointestinal bleeding caused by ulcer disease or gastric mucosal erosion. In the acute phase of the disease, it is generally advocated to take one dose in the morning and one in the evening, and after the disease has subsided, it is changed to a maintenance dose every night.