Diabetic patients have their own characteristics, such as abnormal metabolism, poor resistance, etc. The incidence of diabetes complicated by tuberculosis is 2-5 times that of non-diabetic patients. As the incidence of diabetes increases, the number of patients with diabetes complicated by tuberculosis is also increasing. Patients with diabetes are more likely to have TB, and when they do, their disease progresses faster and is more difficult to treat than TB patients with normal blood sugar. Why is it more difficult to control TB in patients with diabetes? 1. Diabetic patients have low cellular immunity. Disorders of sugar, protein and fat metabolism, malnutrition, reduced antibody formation and low cellular immune function in the body make TB infected patients susceptible to disease and worsen TB lesions. 2, diabetic patients with increased acidity in the body. Blood sugar and tissue containing sugar is high, sugar is further decomposed into acidic substances, tuberculosis bacteria for acid-resistant bacteria, providing favorable conditions for the reproduction and growth of tuberculosis bacteria. 3, increased triacylglycerol in diabetic patients. Sugar metabolism disorders, fat decomposition, triacylglycerol increase, the latter is conducive to the growth and reproduction of tuberculosis bacteria. 4, diabetic patients with reduced respiratory resistance. Metabolic disorders lead to impaired liver function, conversion of vitamin A dysfunction, is vitamin A deficiency, causing reduced resistance of the respiratory mucosa, which is conducive to the reproduction of tuberculosis bacteria. 5, diabetic patients with poor anti-tuberculosis treatment. Diabetic patients can be complicated by multiple organ pathologies, such as liver and kidney dysfunction, which can cause difficulties in the application of anti-tuberculosis drugs and can affect the efficacy of tuberculosis treatment. The tuberculosis itself and anti-tuberculosis drugs also have a negative effect on glucose metabolism and hypoglycemic drugs, which can also aggravate diabetes. Therefore, TB patients with diabetes mellitus have rapidly progressing TB lesions, easily form cavities, excrete large amounts of bacteria, are not easily converted, and their blood sugar is less easily controlled. Prevention and treatment have their to draw attention.