The treatment of hepatic encephalopathy varies from person to person, and there is no “best” statement. The treatment includes treating the primary disease, removing the causative factors, reducing the generation and absorption of intestinal toxins, using ammonia-reducing medications, and restoring the normal neurotransmitter medications, and so on. 1. Treatment of primary diseases: e.g. severe hepatitis, cirrhosis, hepatocellular carcinoma, etc. 2. Remove the triggers: use cautiously or prohibit anesthesia, analgesia, sleeping, sedation and other drugs, such as diazepam. Avoid large amount of potassium diuresis and release of ascites. 3. Reduce the generation and absorption of intestinal toxins. (1) Adjust the diet: abstain from protein at the beginning, and gradually increase the protein after waking up. (2) Clean the intestinal tract: use enema or diarrhea to remove the accumulation of food and blood in the intestines. (3) Inhibit the growth of intestinal bacteria: take kanamycin and neomycin orally. (4) Lactulose: oral lactulose can reduce the formation and absorption of ammonia in the intestine. 4. Use of ammonia-lowering drugs (1) Sodium glutamate and potassium glutamate: glutamate can directly combine with ammonia in the blood to form glutamine, which is excreted through the kidneys. (2) Arginine: Arginine can promote the ornithine cycle in the liver and remove ammonia. (3) L-Ornithine-L-Menthionine: Ornithine is directly involved in the urea cycle and accelerates urea synthesis. It is contraindicated in severe renal failure. 5. Drugs to restore normal neurotransmitters (1) Levodopa: Levodopa can form dopamine in the brain to replace the pseudo mediators to treat chronic hepatic coma. (2) Bromocriptine: It can agonize dopamine receptors. Patients with hepatic encephalopathy should not use medication on their own, but should go to the hospital in time and standardize the treatment under the guidance of the doctor.