Hypercholestasis in pregnant women, also known as cholestasis during pregnancy, causes yellow staining of the skin and sclera. This condition has a greater impact on the fetus and can easily cause premature birth, low birth weight, fetal distress, and neonatal asphyxia. Once a pregnant woman develops itchy skin, she should be promptly examined. An early diagnosis is reliably indicated by an increase in serum conjugated bile acids before the appearance of itching or an increase in serum glutamic aminotransferase. There are no specific medications available for treatment. To prevent postpartum hemorrhage in pregnant women, vitamin K supplements should be taken before surgery.